Cholesterol Efflux

The Medicines Company Announces Investigational Lipid Modulating Agent, MDCO-216, Phase 1 Data Published In European ...
The Medicines Company today announced that the European Heart Journal – Cardiovascular Pharmacotherapy has published results of its Phase 1 study for MDCO-216, a compound under development for the reduction of atherosclerotic plaque burden and related life-threatening cardiovascular events in patients with coronary artery disease . ... Read News

Uremia Alters HDL Composition And cholesterol Efflux Capacity
MEETING ABSTRACT Open Access Uremia alters HDL composition and cholesterol efflux capacity Michael Holzer1, Ruth Birner-Grünberger2, Tatjana Stojaković3, Dalia El-Gamal1, Veronika Binder1, ... Fetch Document

APOA2 - Wikipedia, The Free Encyclopedia
Function. This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II ... Read Article

Ab196985 Assay Kit (Cell-based) Cholesterol Efflux - Abcam
Version 1 Last Updated 18 March 2015 Instructions for Use A high-throughput screening assay for measuring cholesterol efflux in cells using fluorescently-labeled cholesterol. ... Fetch Doc

Walnut Oil Increases cholesterol Efflux Through Inhibition Of ...
RESEARCH Open Access Walnut oil increases cholesterol efflux through inhibition of stearoyl CoA desaturase 1 in THP-1 macrophage-derived foam cells ... Access This Document

Apolipoproteins, Membrane cholesterol Domains, And The ...
Apolipoproteins, membrane cholesterol domains, and the regulation of cholesterol efflux George H. Rothblat,’ Florence H. Mahlberg,Z William J. Johnson, and Michael C. Phillips ... Get Doc

Cholesterol Efflux To Apolipoprotein AI Involves Endocytosis ...
Efflux to apoE (10). However, if the cAMP analogue was added during a 16-hr pretreatment period and again during the chase phase, induced cholesterol efflux was apparent by 2 hr, ... Doc Viewer

Cholesterol Efflux From FuSAH Hepatoma Cells Induced By ...
ELSEVIER Atherosclerosis 127 (1996) 245-253 ATHEROSCLEROSIS Cholesterol efflux from FuSAH hepatoma cells induced by plasma of subjects with or without coronary artery disease and ... Content Retrieval

Cholesterol Efflux Assay Kit (Cell-based) - Abcam.com
Product name Cholesterol Efflux Assay Kit (Cell-based) Detection method Fluorescent Sample type Serum, Purified protein Assay type Cell-based (quantitative) ... View Doc

Cholesterol Efflux Via ATP-binding Cassette Transporter A1 ...
ARTICLE Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell ... Read More

CHOLESTEROL EFFLUX IN ADIPOSE TISSUE - ResearchGate
CHOLESTEROL EFFLUX IN ADIPOSE TISSUE By PHILIP BENJAMIN VERGHESE Bachelor of Science in Chemistry University of Pune Pune, India 1995 Master of Science in Biochemistry ... Read Content

Control Of Cellular cholesterol Efflux By The Nuclear ...
Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRa Asha Venkateswaran*†, Bryan A. Laffitte†‡, Sean B. Joseph§, Puiying A. Mak*, Damien C. Wilpitz‡, Peter A. Edwards*¶i, ... View Doc

Ceramide Enhances cholesterol Efflux To Apolipoprotein A-I By ...
Ceramide enhances cholesterol efflux 2 ABSTRACT It is widely accepted that functional ABCA1 is critical for the formation of nascent high-density lipoprotein (HDL) particles. ... Content Retrieval

Regulation Of Reverse cholesterol Transport - A Comprehensive ...
In enhanced efflux of cholesterol [29]. However, such a manipulation is also likely to impact the cholesterol load-ing of the macrophages used in the RCT experiment. Nevertheless, in vivo the movement of radiolabeled ... Fetch Content

Apolipoprotein C2 - Wikipedia, The Free Encyclopedia
Lab tests will show elevated blood levels of triglycerides, cholesterol, and chylomicrons [2] Interactive pathway map. Click on genes, proteins and metabolites below to link to respective articles. [§ 1] ... Read Article

Decreased Cholesterol Efflux Capacity And Atherogenic Lipid ...
Decreased Cholesterol Efflux Capacity and Atherogenic Lipid Profile in Young Women With PCOS Andrea Roe, Jennifer Hillman, Samantha Butts, Mathew Smith, Daniel Rader, ... Doc Viewer

Mitochondrial Function Is Involved In Regulation Of ...
RESEARCH Open Access Mitochondrial function is involved in regulation of cholesterol efflux to apolipoprotein (apo)A-I from murine RAW 264.7 macrophages ... Content Retrieval

AHA Scientific Sessions Chicago - My.americanheart.org
Discussant: HDL Cholesterol efflux capacity and incident CV events in the Dallas Heart Study AHA Scientific Sessions Chicago November 18, 2014. Daniel J. Rader, MD ... Document Viewer

Aramchol - Wikipedia, The Free Encyclopedia
Aramchol activates cholesterol efflux by stimulating (2 to 4-fold) the ABCA1 transporter, a universal cholesterol export pump present in all cells5. ... Read Article

Cherry Juice Concentrate Cures Gout And More? - About.com
Cherry Juice Concentrate Cures Gout and More? FDA Warns Companies About Unproven Claims. By Carol Eustice. Arthritis & Joint Conditions Expert Share Pin Tweet Submit Stumble Post Share Sign Up for our Free Newsletters Thanks, You're in! ... Read Article

Charité Clinical Journal Club By Fred Luft - 24.12.2014 - YouTube
The N Engl J Med image of the week shows a conventional posterior-anterior chest roentgenogram showing a strange right cardiac silhouette with a fluid level to the right of the sternum. You are offered aortic aneurysm, aortic coarctation, diaphragmatic hernia, esophageal diverticulum ... View Video

Cholesterol Efflux And Reverse Cholesterol Transport
Cholesterol Efflux and Reverse Cholesterol Transport Elda Favari, Angelika Chroni, Uwe J.F. Tietge, Ilaria Zanotti, Joan Carles Escola`-Gil, and Franco Bernini ... Get Content Here

Cholesterol Efflux To Apolipoprotein AI Involves Endocytosis ...
Cholesterol efflux from human fibroblasts to HDL, and binding of HDL to the cells, also were stimulated by cAMP analogues or by reagents that increase endogenous cAMP (25). Addi- tionally, the apolipoprotein endocytosis and resecretion path- ... Return Document

Regulation And Mechanisms Of Macrophage cholesterol Efflux
Bly the optimal substrates for SR-BI. In summary, ABCA1 may play the major role in initiating cholesterol efflux from macrophages and other cells to lipid-poor ... Access Doc

Genetics Of Cholesterol Efflux - ResearchGate
GENETICS (AJ MARIAN, SECTION EDITOR) Genetics of Cholesterol Efflux Iulia Iatan & Aurélien Palmyre & Sarah Alrasheed & Isabelle Ruel & Jacques Genest # Springer Science+Business Media, LLC 2012 ... Retrieve Document